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Improved economics of HBsAg screening with commercial radioimmunoassay reagents.
  1. R Hopkins,
  2. S Ross,
  3. T Jordan,
  4. A D Watt


    Commercial 125I anti-HBs was processed to yield a sixfold improvement in economy without significant loss of sensitivity or specificity. Additional polystyrene beads were coupled with commercially supplied anti-HBs. The modified assay (Mod-RIA) was compared with commercial RIA, EIA, and RPHA using established HBsAg panels. Mod-RIA was also compared with HEPATEST (RPHA) for screening 71 200 fresh blood donations during an 11.5-month period.

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