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Quantitative study of the immunoglobulin-containing cells in trephine samples of bone marrow
  1. J Crocker,
  2. RC Curran
  1. Department of Pathology, The Medical School, Birmingham B15 2TJ


    Immunoglobulin (Ig) was demonstrated in paraffin sections of 12 trephine bone marrow biopsies by means of the unlabelled antibody peroxidase-antiperoxidase (PAP) method. The Ig-containing cells, which were counted with the Reichert-Jung (Kontron) MOP-AMO3 user-controlled image-analyser, were found to constitute approximately 4·2% of all the nucleated cells in the marrow, a figure significantly higher than those reported by previous workers.

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