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Combination of minocycline and rifampicin against methicillin- and gentamicin-resistant Staphylococcus aureus
  1. E Yourassowsky,
  2. MP Van Der Linden,
  3. MJ Lismont,
  4. F Crokaert
  1. Hôpital Universitaire Brugmann, Service de Biologie Clinique, 1020 Bruxelles, Belgique


    Methicillin- and gentamicin-resistant Staphylococcus aureus may remain sensitive to minocycline and to rifampicin. A study of growth curves has shown that at inhibitory concentrations (0·4 μg/ml), minocycline prevents the development of mutants resistant to rifampicin.

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