Article Text

Download PDFPDF

Malignant fibrous histiocytomas of salivary glands
  1. E Benjamin,
  2. S Wells,
  3. H Fox,
  4. NL Reeve,
  5. F Knox
  1. Departments of Pathology, University of Manchester, Manchester M13 9PT
  2. Stepping Hill Hospital, Stockport, Cheshire


    The light microscopic, immunohistological and ultrastructural findings in two cases of malignant fibrous histiocytoma arising in salivary glands are presented and the features of seven previously reported cases are reviewed. This neoplasm is extremely rare in this site and may pose problems in diagnosis. It has to be distinguished from other spindled cell tumours, in particular from epithelial tumours of predominantly spindled cell pattern; immunohistological markers for histiocytic cells may be of value. The histogenesis of this neoplasm is controversial but our electron microscopic findings support an origin from mesenchymal cells which differentiate along a broad fibrohistiocytic spectrum.

    Statistics from

    Request Permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.