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Study of nuclear diameters in non-Hodgkin's lymphomas
  1. J Crocker,
  2. EL Jones,
  3. RC Curran
  1. Department of Pathology, The Medical School, University of Birmingham, Edgbaston, Birmingham B15 2TJ


    The mean maximum nuclear diameter (Dmax) in 21 cases of non-Hodgkin's lymphoma (NHL) has been determined, using the Reichert-Jung (Kontron) MOP-AMO3 user-controlled image analyser. Nuclear diameters of high-grade malignancy NHL were found to be considerably greater than those of low-grade malignancy lymphomas, although there was some overlap of their ranges. These findings confirm objectively subjective estimates of nuclear size in NHL. The relative usefulness of the user-controlled (interactive) image analyser for the measurement of nuclei in tissue sections is compared with that of a fully automatic machine.

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