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Giant cell myocarditis: evidence for the macrophage origin of the giant cells.
  1. J M Theaker,
  2. K C Gatter,
  3. A Heryet,
  4. D J Evans,
  5. J O McGee


    In order to elucidate the origin of giant cells in giant cell myocarditis a case has been studied immunohistologically using monoclonal antibodies against a variety of antigens, including those associated with muscle and macrophages. The results strongly suggest that the giant cells are derived from macrophages rather than the muscle cells.

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