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Importance of showing HBsAg and HBcAg positivity in the liver for better aetiological definition of chronic liver disease.
  1. L Cuccurullo,
  2. M Rambaldi,
  3. G Iaquinto,
  4. F Ferraraccio,
  5. L Ambrosone,
  6. N Giardullo,
  7. A De Vita


    Serum and tissue hepatitis B virus (HBV) markers were compared in 35 alcoholic and 23 non-alcoholic subjects affected by chronic liver disease. Seventeen point one per cent of alcoholic and 21.7% of non-alcoholic subjects had HBV tissue markers, but not serum markers, for this virus. It is therefore concluded that showing the presence of HBV tissue markers permits a better aetiological definition of hepatitis B surface antigen (HBsAg) negative chronic liver disease, both in alcoholic and non-alcoholic subjects.

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