You are here

Article Text

Article menu

Download PDFPDF

Research Article
Expression of CEA, CA125, CA19-9 and human milk fat globule membrane antigen in ovarian tumours.
Free
  1. F Macdonald,
  2. R Bird,
  3. H Stokes,
  4. B Russell,
  5. J Crocker
  1. Surgical Immunology Unit, Queen Elizabeth Hospital, Birmingham.

    Abstract

    The expression of five different antigens in ovarian tumours was studied by means of an immunohistochemical test with anti-CEA, HMFG1 and HMFG2, NS19-9 and OC125 antibodies. Considerable variation was noted not only between different histological types and between tumours of one type but also between areas in a single tumour. HMFG1 and HMFG2 were the most reactive of all the antibodies; NS19-9 and OC125 were expressed by different populations of cells. It is concluded that specific combinations of antibodies are more effective both for the monitoring of ovarian cancer as well as for immunodiagnosis and treatment, than any single one used.

    http://dx.doi.org/10.1136/jcp.41.3.260

    Statistics from Altmetric.com

      Request Permissions

      If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.