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Cytogenetic analysis of a granulocytic sarcoma in a patient without systemic leukaemia.
  1. L R Adam,
  2. B Angus,
  3. P Carey,
  4. E V Davison
  1. Department of Human Genetics, University of Newcastle upon Tyne.


    Granulocytic sarcoma is a rare complication of leukaemia. Occasionally it presents before the development of systemic leukaemia when diagnosis may be difficult. A case of granulocytic sarcoma occurring in a patient with no overt evidence of leukaemia, but in whom cytogenetic analysis of the bone marrow showed a clonal t(12;13) translocation, is reported. Cytogenetic analysis of tissues in this disease may indicate evidence of systemic disease before overt morphological changes.

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