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Rapidly fatal necrotising fasciitis caused by Streptococcus pyogenes.
  1. P M Donaldson,
  2. B Naylor,
  3. J W Lowe,
  4. D R Gouldesbrough
  1. Department of Clinical medicine, University of Leeds.


    AIMS--To describe the morbid anatomical and bacteriological features in a series of five cases of rapidly fatal Streptococcus pyogenes necrotising fasciitis. METHODS--Post mortem and bacteriological examinations were made of five patients dying within 48 hours from rapidly fatal necrotising fasciitis. RESULTS--All five cases died rapidly from a toxic Streptococcus toxin syndrome as a result of developing necrotising fasciitis following trivial injury. CONCLUSIONS--Necrotising fasciitis caused by Streptococcus pyogenes infection can be rapidly fatal. This is probably the result of a toxic shock syndrome. Rapid, early diagnosis and swift and probably empirical treatment is required to avoid a fatal outcome.

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