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Involvement of the appendix in pseudomembranous colitis.
  1. J D Coyne,
  2. P A Dervan,
  3. N Y Haboubi
  1. Department of Histopathology, South Manchester University Hospitals NHS Trust.


    Pseudomembranous colitis (PMC) is an inflammatory disorder usually limited to the large intestine and is the consequence of antibiotic associated Clostridium difficile overgrowth with production of its toxin. It has a characteristic gross and microscopic appearance. PMC-like changes, usually associated with peri-operative hypotension and with more extensive gastrointestinal tract involvement, have also been described. In neither clinical setting has pseudomembranous appendicitis been recorded. A case of pseudomembranous appendicitis in a 76 year old woman is described.

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