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Lymphoma associated bone marrow necrosis with raised anticardiolipin antibody.
  1. P T Murphy,
  2. M Sivakumaran,
  3. M C Casey,
  4. A Liddicoat,
  5. J K Wood
  1. Department of Haematology, Leicester Royal Infirmary, UK.


    A case of high grade B cell lymphoma presented with bone marrow necrosis, followed by development of extensive marrow fibrosis, the evolution of which was documented by serial magnetic resonance imaging and bone marrow trephine histology. A markedly raised anticardiolipin antibody titre at diagnosis suggests that lymphoma associated antiphospholipid syndrome may have contributed to the aetiology of the bone marrow necrosis.

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