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Haemoglobin Le Lamentin (alpha 20 (B1) His-->Gln) in a British family: identification by electrospray mass spectrometry.
  1. T M Reynolds,
  2. F McMillan,
  3. A Smith,
  4. A Hutchinson,
  5. B Green
  1. Queen's Hospital, Burton-on-Trent, Staffordshire, UK Clinical Chemistry Department.


    The first identification of haemoglobin Le Lamentin (alpha 20 (B1) His-->Gln) in a British patient is described. The patient was a 69 year old asymptomatic white male being screened for diabetes, whose blood was undergoing its first ever analysis for glycated haemoglobin using a Glycomat II analyser. Identification of the haemoglobin variant was by electrospray mass spectrometry.

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