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Primary large cell neuroendocrine carcinoma of the presacral region
  1. P Theunissen1,
  2. M Fickers2,
  3. R Goei3
  1. 1Department of Pathology, Atrium Medical Centre, PO Box 4446, 6401CX Heerlen, The Netherlands
  2. 2Department of Internal Medicine, Atrium Medical Centre
  3. 3Department of Radiology, Atrium Medical Centre
  1. Dr Theunissen p.theunissen{at}gozl.nl

Abstract

A 7 cm diameter presacral tumour, not related to the intrapelvic organs, was found in a 51 year old woman. The needle biopsy showed a poorly differentiated large cell carcinoma. The patient died of urosepsis after chemotherapy. Postmortem examination revealed no other primary or metastatic tumour. Histological examination of the presacral tumour showed a large cell carcinoma with a trabecular pattern and strong immunoreactivity for neuroendocrine markers. The tumour was finally classified as a primary large cell neuroendocrine carcinoma of the presacral region.

  • neuroendocrine carcinoma
  • presacral region

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