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Active aortitis in relapsing polychondritis
  1. A-G A Selim1,
  2. L G Fulford1,
  3. R H Mohiaddin2,
  4. M N Sheppard1
  1. 1Department of Histopathology, Royal Brompton Hospital, Imperial College, School of Medicine, Sydney Street, London SW3 6NP, UK
  2. 2Magnetic Resonance Unit, Royal Brompton Hospital
  1. Dr Sheppard m.sheppard{at}rbh.nthames.nhs.uk

Abstract

Relapsing polychondritis (RP) is a rare inflammatory multiorgan disorder affecting cartilaginous structures and other connective tissues. Serious cardiovascular complications have been reported in patients with RP, the most frequent being aortic or mitral regurgitation and aortic aneurysms. Aortitis is a very rare complication. An unusual case of active aortitis in a patient with RP, despite intensive immunosupressive treatment, is described with a special emphasis on the pathological findings.

  • relapsing polychondritis
  • aortitis
  • aortic regurgitation

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