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The incidence of primary varicella zoster virus infection (VZV) in young adults and pregnant women has risen in recent years and is accompanied by a greater risk of serious complications.1 VZV disease in the elderly usually presents as shingles, as a result of secondary reactivation of latent infection, and can be treated successfully with early antiviral therapy. We report a case of fatal primary infection in an elderly man.J Clin Pathol 2001;54:494–496
A 66 year old Bangladeshi man with fibrosing alveolitis and non-insulin dependent diabetes mellitus was admitted to hospital with increasing shortness of breath for one week. He was a smoker and had been well controlled on 25 mg of prednisolone daily for the previous two months.
On admission he was febrile (38.5°C), tachypnoeic (50 breaths/minute), and hypotensive (blood pressure, 85/60 mm Hg), with severe mucosal candidiasis. An extensive maculopapular rash, present for three days, was noted and thought to be consistent …