Löscher W, ed. ($185.00.) Birkhäuser, 1999. ISBN 376435836.

Valproate has been the subject of over 5000 publications. It was discovered accidentally: it was used as a vehicle for some water insoluble compounds under investigation and found to have an independent anticonvulsant effect. The first clinical reports appeared in 1964. It can justifiably claim its place in the “milestones in drug …