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Metastatic rectal adenocarcinoma to the liver associated with focal nodular hyperplasia
  1. P J Nisar1,
  2. A M Zaitoun2,
  3. A Damera3,
  4. Z Hodi2,
  5. G M Tierney1,
  6. I J Beckingham1
  1. 1Section of Surgery, Queen's Medical Centre, Nottingham NG7 2UH, UK
  2. 2Department of Histopathology, Queen's Medical Centre
  3. 3Department of Radiology, Queen's Medical Centre
  1. Correspondence to:
 Dr A M Zaitoun, Department of Histopathology, University Hospital, Queen's Medical Centre, Nottingham NG7 2UH, UK;


A 45 year old female patient underwent right hemihepatectomy for metastatic rectal adenocarcinoma. Preoperative imaging demonstrated an area of focal nodular hyperplasia (FNH) in segment VIII and metastatic carcinoma in segment VI of the liver. Gross and microscopic examination of the former lesion showed features typical of FNH with an intralesional metastatic adenocarcinoma. To the best of our knowledge, this is the first reported case of metastatic adenocarcinoma located within a lesion of FNH. The possibility of a pathogenetic association behind this occurrence is discussed.

  • adenocarcinoma
  • focal nodular hyperplasia
  • liver neoplasms
  • magnetic resonance imaging
  • rectal neoplasm
  • FNH, focal nodular hyperplasia
  • MRI, magnetic resonance imaging

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