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Tumour suppressor genes do not regulate the cell cycle

https://doi.org/10.1136/jcp.56.1.11

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    A study of the effects of hamartin and tuberin on cell growth suggests that tuberin acts as a tumour suppressor gene—but not by regulating the cell cycle. The researchers induced transient overexpression of hamartin and tuberin in cell cultures from a human kidney (HEK293) cell line by transfection. They …

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