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Serum Ro52 antibody denotes connective tissue disease

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A hitherto unrecognised subgroup of patients can now be identified, since the discovery of another, independent, serum marker for connective tissue diseases. Eighteen serum samples among more than 1700 tested routinely for antinuclear antibodies (ANAs), denoting connective tissue diseases, showed specificity solely for 52 kDa protein Ro52 and no cross reactivity …

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