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Malignant transformation of a recurrent vestibular schwannoma
  1. J S Wilkinson,
  2. H Reid,
  3. G R Armstrong
  1. Department of Histopathology, Hope Hospital, Stott Lane, Salford, M6 8HD, UK;

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    Malignant nerve sheath tumours are uncommon tumours, particularly those that affect cranial nerves. They are most frequently seen within the context of neurofibromatosis type II. Malignant transformation of benign cranial nerve sheath tumours has been reported on very few occasions.1–4 We report a case of malignant nerve sheath tumour arising as a recurrent tumour at the site of a previous benign schwannoma.

    Tissue was received from the resection of a mass surrounding and involving the right acoustic nerve of a 53 year old man who had previously undergone resection of a tumour involving the same site. Histology from the previous resection, seven years …

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