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Childhood onset SLE found to be associated with oestrogen receptor α gene polymorphism

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    For the first time, children developing systemic lupus erythematosus (SLE) under the age of 16 have been found to have significantly different polymorphisms of the Pvull and Xbal genes for oestrogen receptor α (ORα) compared to those developing the disease over the age of 16.

    In a case-control study …

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