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Benign mixed tumour of the skin with extensive ossification and marrow formation: a case report
  1. R Awasthi1,
  2. D Harmse1,
  3. D Courtney2,
  4. C B A Lyons1
  1. 1Department of Histopathology, Derriford Hospital, Derriford Road, Plymouth PL6 8DH, UK
  2. 2Department of Maxillofacial Surgery, Derriford Hospital
  1. Correspondence to:
    Dr R Awasthi
    Department of Histopathology, Derriford Hospital, Derriford Road, Plymouth PL6 8DH, UK;


Benign mixed tumour of the skin (chondroid syringoma) is an uncommon skin adnexal tumour, usually presenting as a slow growing solitary painless nodule. The morphological appearances are similar to those of a pleomorphic adenoma of the salivary gland. Hair matrix and sebaceous differentiation can be seen in some lesions. Focal ossification is a rare finding. This report presents a case of a similar tumour arising in the cheek of a 43 year old white man, showing extensive ossification. Clinical, radiological, and pathological correlation and diagnosis proved to be difficult preoperatively. Only two cases of a benign mixed tumour with pronounced ossification have been reported so far, both in Japanese patients. This is the first reported case seen in a white man. Awareness of these lesions will avoid potential diagnostic pitfalls.

  • benign mixed tumour
  • chondroid syringoma
  • ossification

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