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Correspondence
Tumorous amyloidosis of the breast associated with disseminated malignant lymphoma
  1. P C W Lui1,
  2. L-M Pang2,
  3. T-T Hlaing3,
  4. G M K Tse4
  1. 1Department of Pathology, United Christian Hospital, Hong Kong
  2. 2Departments of Diagnostic Radiology and Organ Imaging, Prince of Wales Hospital, Chinese University of Hong Kong, Hong Kong
  3. 3Department of Pathology, Kwong Wah Hospital, Kowloon, Hong Kong
  4. 4Departments of Anatomical and Cellular Pathology, Prince of Wales Hospital, Chinese University of Hong Kong; garytse@cuhk.edu.hk

    https://doi.org/10.1136/jcp.2003.012062

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      We report a 77 year old woman with a 14 year history of lymphoplasmacytic lymphoma initially involving the parotid gland, cervical lymph node, and hilar lymph node. She was treated with chlorambucil but the disease ran a protracted course with eventual multiorgan dissemination and required repeated chemotherapy. This time, she presented with bilateral hard, non-tender breast lumps for three months. The clinical diagnosis was lymphoma infiltration versus breast carcinoma. Mammographic examination showed a 2 cm, medium density, well circumscribed mass in the left breast and a 0.5 cm nodule of similar characteristics with macrocalcifications in the right breast.

      Biopsy from the right breast mass showed amyloid deposits with foreign body giant …

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