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We read Dr Cserni’s review of nodal staging for colorectal cancer with interest.1 We have recently performed a multivariate analysis of factors affecting lymph node yield after resection of rectal cancer (unpublished data, 2003) and found positive predictors to be tumour size, pT stage, Dukes’s stage, number of involved lymph nodes, and examination by a histopathologist with a special interest in gastrointestinal malignancy. These are all mentioned by Dr Cserni in his excellent article. Interestingly, although 29 of our patients underwent neoadjuvant treatment (18 short course radiotherapy; 11 long course chemoradiotherapy) this did not appear to affect lymph node yield, despite previous publications to the …