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Case report
Treatment difficulties of a listerial rhombencephalitis in an adult patient allergic to penicillins
  1. G A Popescu1,
  2. M Saquepée2,
  3. D Poisson3,
  4. T Prazuck4
  1. 1Infectious Diseases Department, Regional Hospital Orléans, France and “Matei Bals” Infectious Diseases Institute, Bucharest, Romania
  2. 2Intensive Care Unit, Regional Hospital Orléans, France
  3. 3Microbiology Department, Regional Hospital Orléans
  4. 4Infectious Diseases Department, Regional Hospital Orléans
  1. Correspondence to:
 G A Popescu
 Str. Brebu, nr.4, bl. T 11, ap. 12, sector 2, Bucharest, Romania; gabrielp9yahoo.com

Abstract

Rhombencephalitis is not a rare presentation of listerial central nervous system infections in healthy adults. This report describes a case with several management difficulties linked to antibiotic related adverse events, pointing to alternative solutions to aminopenicillins. In addition, the role of dexamethasone in the management of inflammation and neurological symptoms is discussed.

  • Listeria monocytogenes
  • rhombencephalitis
  • antimicrobial treatment
  • adverse events
  • dexamethasone
  • CNS, central nervous system
  • CT, computed tomography
  • CSF, cerebrospinal fluid
  • RE, rhombencephalitis
  • TMP/STX, trimethoprim-sulfamethoxazole
  • WBC, white blood cell count

https://doi.org/10.1136/jcp.2003.014738

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