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Rat bite fever caused by Streptobacillus moniliformis in a child: human infection and rat carriage diagnosed by PCR
  1. J-M Andre1,
  2. A M Freydiere2,
  3. Y Benito3,
  4. A Rousson1,
  5. S Lansiaux1,
  6. A Kodjo4,
  7. C Mazzocchi5,
  8. J-C Berthier1,
  9. F Vandenesch3,
  10. D Floret6
  1. 1Service de Réanimation Pédiatrique, Hôpital Debrousse, Hospices Civils de Lyon, 69322 Lyon cedex 5, France
  2. 2Laboratoire de Bactériologie, Hôpital Debrousse, Hospices Civils de Lyon
  3. 3Laboratoire de Bactériologie, Hôpital Cardiologique Louis Pradel, Hospices Civils de Lyon 69677
  4. 4Ecole Nationale Vétérinaire de Lyon, 69280 Marcy l’Etoile, France
  5. 5Service de Pédiatrie, Pneumologie et Allergologie, Hôpital Debrousse, Hospices Civils de Lyon
  6. 6Service de Réanimation Pédiatrique, Hôpital Edouard Herriot, Hospices Civils de Lyon, 69437 Lyon, France
  1. Correspondence to:
 Dr A-M Freydière
 Laboratoire de Microbiologie, Hôpital Debrousse, Hospices Civils de Lyon, 29 Rue Soeur Bouvier, 69322 Lyon cedex 5, France; anne-marie.freydierechu-lyon.fr

Abstract

A child owning pet rats developed an eruptive fever with blisters, polyarthritis, and spectacular desquamation of the hands. Streptobacillus moniliformis was identified after culture of the child’s blister fluid and was detected in rat samples by molecular methods. Such detection in the pet of a human victim of rat bite fever has not been reported previously.

  • PCR, polymerase chain reaction
  • RBF, rat bite fever
  • rat bite fever
  • Streptobacillus moniliformis
  • pet rat
  • hand desquamation
  • molecular diagnosis

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