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Pure testicular carcinoid associated with intratubular germ cell neoplasia
  1. J Merino1,
  2. A Zuluaga2,
  3. F Gutierrez-Tejero2,
  4. M del Mar Serrano1,
  5. S Ciani1,
  6. F F Nogales1
  1. 1Department of Pathology, University Hospital, E-18012 Granada, Spain
  2. 2Department of Urology, University Hospital
  1. Correspondence to:
    Professor F F Nogales
    Departamento de Anatomía Patológica, Facultad de Medicina, 18012 Granada, Spain;


This case report describes for the first time a case of pure testicular carcinoid preaortic lymph node metastases in a 25 year old patient with carcinoid syndrome. The simultaneous occurrence of intratubular germ cell neoplasia in the surrounding testicular tissue was identified by OCT4 and placental-like alkaline phosphatase positivity. This confirmed that the tumour had a germ cell origin in the testis, rather than being a metastasis from an extragenital carcinoid.

  • ITGCN, intratubular germ cell neoplasia
  • PLAP, placental-like alkaline phosphatase
  • testis
  • carcinoid
  • intratubular germ cell neoplasia
  • carcinoma in situ

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  • The patient gave his informed consent for this case report to be published