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CA IV may be target antigen in autoimmune pancreatitis

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Japanese researchers have uncovered a serum antibody that may prove to be a marker for disease affecting multiple exocrine glands—like autoimmune pancreatitis (AIP) and Sjögren’s syndrome (SS). The target antigen—carbonic anhydrase isozyme IV (CA IV)—is commonly found in exocrine gland epithelia.

The antibody was significantly more common …

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