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Case report
ALK positive inflammatory myofibroblastic tumour of the pineal region
  1. A J Clarke1,
  2. T S Jacques2,
  3. M J Galloway2,
  4. M Thom2,
  5. N D Kitchen3,
  6. G T Plant1
  1. 1Department of Neurology, National Hospital for Neurology and Neurosurgery, Queen Square, London WC1N 3BG, UK
  2. 2Department of Neuropathology, National Hospital for Neurology and Neurosurgery
  3. 3Department of Neurosurgery, National Hospital for Neurology and Neurosurgery
  1. Correspondence to:
 Dr A J Clarke
 Department of Neurology, National Hospital for Neurology and Neurosurgery, Queen Square, London WC1N 3BG, UK; alexactualmedia.com

Abstract

Inflammatory myofibroblastic tumours (IMTs) are an uncommon spindle cell neoplasm with a dense inflammatory infiltrate, usually encountered in children. IMTs of the central nervous system are extremely rare. This report describes the case of an IMT in a 61 year old man, in the pineal region. The tumour was completely excised, and immunohistochemistry demonstrated anaplastic lymphoma kinase 1 expression. There was no tumour recurrence during 18 months of follow up. Our case extends both the age range and sites of occurrence of this rare tumour.

  • ALK, anaplastic lymphoma kinase
  • IMT, anaplastic lymphoma kinase
  • inflammatory myofibroblastic tumour
  • inflammatory pseudotumour
  • anaplastic lymphoma kinase
  • anaplastic lymphoma kinase

https://doi.org/10.1136/jcp.2004.022947

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    Footnotes

    • The patient gave his informed consent for this case to be reported.