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ALK positive inflammatory myofibroblastic tumour of the pineal region

Abstract

Inflammatory myofibroblastic tumours (IMTs) are an uncommon spindle cell neoplasm with a dense inflammatory infiltrate, usually encountered in children. IMTs of the central nervous system are extremely rare. This report describes the case of an IMT in a 61 year old man, in the pineal region. The tumour was completely excised, and immunohistochemistry demonstrated anaplastic lymphoma kinase 1 expression. There was no tumour recurrence during 18 months of follow up. Our case extends both the age range and sites of occurrence of this rare tumour.

  • ALK, anaplastic lymphoma kinase
  • IMT, anaplastic lymphoma kinase
  • inflammatory myofibroblastic tumour
  • inflammatory pseudotumour
  • anaplastic lymphoma kinase
  • anaplastic lymphoma kinase

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