Figure 9

Figure 9

 High-grade dysplasia in Barrett’s oesophagus with a focal area highly suggestive of intramucosal adenocarcinoma. In the centre of the field is a proliferation of small glands in a back-to-back configuration, with little intervening lamina propria, which is difficult to explain on the basis of involvement of pre-existing crypts. There is a suggestion of isolated single cells in the lamina propria as well.