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Best practice in primary care pathology: review 3


This best practice review examines four series of common primary care questions in laboratory medicine: (i) “minor” blood platelet count and haemoglobin abnormalities; (ii) diagnosis and monitoring of anaemia caused by iron deficiency; (iii) secondary hyperlipidaemia and hypertriglyceridaemia; and (iv) glycated haemoglobin and microalbumin use in diabetes. The review is presented in question–answer format, referenced for each question series. The recommendations represent a précis of guidance found using a standardised literature search of national and international guidance notes, consensus statements, health policy documents and evidence-based medicine reviews, supplemented by Medline Embase searches to identify relevant primary research documents. They are not standards, but form a guide to be set in the clinical context. Most of the recommendations are based on consensus rather than evidence. They will be updated periodically to take account of new information.

  • ADA, American Diabetes Association
  • CVD, cardiovascular disease
  • DCCT, Diabetes Control and Complications Trial
  • GMS, General Medical Services
  • HbA1c, glycated haemoglobin
  • LDL, low-density lipoprotein
  • MCV, mean cell volume
  • NICE, National Institute for Health and Clinical Excellence

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