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Lung cancer is the second most common cancer in the UK, accounting for one in seven new cancer diagnoses and 22% of cancer deaths (http://info.cancerresearchuk.org/cancerstats). Small-cell carcinoma (SCC) accounts for 20% of lung cancers, with most of these presenting at an advanced stage and being treated using chemotherapy and radiotherapy. About 25% of patients do not respond to chemotherapy. The reasons for this are uncertain and may be because of the heterogeneity of the disease or inaccurate pathological diagnosis, which …
Competing interests: None declared.