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Squamous metaplasia of the rectum in a case of Hirschprung’s disease: a coincidence or an association
  1. V Mahesha1,
  2. K Sehgal1,
  3. U N Saikia1,
  4. K L N Rao2
  1. 1Department of Histopathology, Postgraduate Institute of Medical Education and Research, Chandigarh, India
  2. 2Department of Pediatric Surgery, Postgraduate Institute of Medical Education and Research
  1. Correspondence to:
 U N Saikia
 Department of Histopathology, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India; umasaikia{at}

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The normal anosquamous junction is located 2.3 cm away from the anal margin and this junctional zone may extend up to a maximum of 1 cm above the dentate line. However, squamous mucosa in the rectum is an abnormal and rare entity. The progression of metaplasia to dysplasia and subsequently to neoplasia is a logical sequence and is well established in the genesis of colorectal, oesophageal and cervical carcinomas. The progression of rectal squamous metaplasia is not established for primary rectal squamous cell carcinoma, although malignant change in rectal squamous metaplasia or leucoplakia has rarely been described.1

A 5-month-old boy, born full term by vaginal delivery, presented with abdominal distension and delayed passage of meconium postnatally. …

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  • Competing interests: None declared.