A single-needle single-site technique for bone marrow aspiration and core biopsy has been compared with a two-needle technique, using 30 randomly selected patients who required these two investigations. In addition, two single-needle techniques were compared, aspirating immediately after penetrating the cortex or, alternatively, aspirating after the needle (without the stilette) had been advanced 20–25 mm. The two-needle technique was found to be superior to either of the single-needle techniques, which often resulted in a biopsy specimen that was denuded of bone marrow cells.
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Funding: The author has not received any financial support for the preparation of this scientific report.
Competing interests: None declared.
I wish to disclose that I am the designer of the bone marrow needles used in this study, and they are commercially available through a manufacturer of medical instrumentation.
Published Online First 2 June 2006
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