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Pseudo-pseudohypercalcaemia, apparent primary hyperparathyroidism and Waldenström's macroglobulinaemia
  1. A Elfatih1,
  2. N R Anderson2,
  3. M N Fahie-Wilson3,
  4. R Gama4
  1. 1Department of Clinical Biochemistry, Whipps Cross University Hospital, Leytonstone, London, UK
  2. 2Department of Clinical Biochemistry, George Elliott Hospital, Nuneaton, UK
  3. 3Department of Clinical Biochemistry, Southend Hospital, Prittlewell Chase, Westcliffe-on Sea, UK
  4. 4Department of Clinical Chemistry, New Cross Hospital, Wolverhampton, UK; Department of Research Institute, Healthcare Sciences, Wolverhampton University, Wolverhampton, UK
  1. Correspondence to:
    Dr A Elfatih
    Department of Clinical Biochemistry, Whipps Cross University Hospital, Leytonstone, London E11 1NR, UK; abubaker.elfatih{at}


An apparent primary hyperparathyroidism was reported due to pseudo-pseudohypercalcaemia in a 74–year-old man with Waldenström’s macroglobulinaemia. It is important to recognise artificially elevated serum calcium levels so as to avoid erroneous diagnosis, unnecessary investigations and potentially inappropriate treatment.

  • CPC, cresolphthalein complexone
  • PSA, prostate-specific antigen

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  • Competing interests: None declared.

  • Informed consent was obtained from the patient described in this report.