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Gene therapy with HGF cDNA in patients on peritoneal dialysis
  1. Y Maeda1,
  2. T Matsuoka2,
  3. K Matsuo2,
  4. Y Naiki2,
  5. M Sakaguchi3,
  6. H Hasegawa3
  1. 1
    Department of Hematology, Kinki University School of Medicine, Kinki University Sakai Hospital, Osaka, Japan
  2. 2
    Department of Nephrology, Kinki University School of Medicine, Kinki University Sakai Hospital, Osaka, Japan
  3. 3
    Kinki University Sakai Hospital, Osaka, Japan
  1. Dr Y Maeda, Department of Hematology, Kinki University School of Medicine, Osaka, Japan; ymaeda{at}med.kindai.ac.jp

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Continuous ambulatory peritoneal dialysis (CAPD) is an effective therapy for the treatment of patients with end-stage renal failure.1 Peritoneal fibrosis is one of the most common morphological changes observed in long-term CAPD patients and includes loss of mesothelial cells and severe accumulation of collagen fibres.2 The prevention of peritoneal fibrosis is necessary for maintenance of long-term CAPD. It has previously been reported that transforming growth factor-beta 1 …

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  • Competing interests: None declared.