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Gene therapy with HGF cDNA in patients on peritoneal dialysis
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Continuous ambulatory peritoneal dialysis (CAPD) is an effective therapy for the treatment of patients with end-stage renal failure.1 Peritoneal fibrosis is one of the most common morphological changes observed in long-term CAPD patients and includes loss of mesothelial cells and severe accumulation of collagen fibres.2 The prevention of peritoneal fibrosis is necessary for maintenance of long-term CAPD. It has previously been reported that transforming growth factor-beta 1 …
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Competing interests: None declared.