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Molecular profile of ductal carcinoma in situ of the breast in BRCA1 and BRCA2 germline mutation carriers
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  • Published on:
    Her2 Neu, BRCA1 or Telomere in Breast Cancer?
    • Professor Pranab Kumar Bhattacharya, Professor of Pathology, In charge of Histopathology unit, in charge Blood Bank &VCCTC, Cytogenetics
    • Other Contributors:
      • Ritwik BhattacharyaRupak Bhattacharya BSc(Cal) MSc(JU) ,Dahlia Mukherjee BA (hons)Miss Upasana Bhattacharya,Mrs.chandrani Dutta BSc(zoology), Dr. Debashis BhattacharyaMs(cal) FRCS(Edin). Diptendra Narayan Sarkar MS(cal) FRCS(EDin) DNB.IPGMER Kol-20, W.B

    Dear Editor,

    Elizabeth H Blackburn and Jack Szostak discovered that a unique DNA sequence in the telomeres protects chromosomes from degradation. Carol Greider and Elizabeth Blackburn identified telomerase, the enzyme that makes telomere DNA. These discoveries explained how the ends of the chromosomes are protected by the telomeres and that they are built by telomerase. If the telomeres are shortened, cells age....

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    Conflict of Interest:
    None declared.