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CD4 expression by mast cells in mastocytosis: a case report
  1. E J Soilleux1,
  2. J Bowling2,
  3. K Hollowood1
  1. 1
    Department of Cellular Pathology, John Radcliffe Hospital, Oxford, UK
  2. 2
    Department of Dermatology, Churchill Hospital, Oxford, UK
  1. Dr E J Soilleux, Department of Cellular Pathology, John Radcliffe Hospital, Oxford OX3 9DU, UK; elizabeth.soilleux{at}


A 59-year-old man presented with a five-year history of an asymptomatic widespread truncal rash. Cutaneous biopsies showed mastocytosis, which was shown to be CD4-positive immunohistochemically. This potential diagnostic pitfall in the discrimination of mastocytosis from a variety of other haematopoietic neoplasms, particularly mycosis fungoides, is discussed.

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  • Competing interests: None.

  • Patient consent: Obtained.