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  • Multiple squamous hyperplastic-fibrous inflammatory polyps of the oesophagus: a new feature of eosinophilic oesophagitis?

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Case report
Multiple squamous hyperplastic-fibrous inflammatory polyps of the oesophagus: a new feature of eosinophilic oesophagitis?
  1. D J Mulder1,
  2. S Gander2,
  3. D J Hurlbut3,
  4. D A Soboleski4,
  5. R G Smith2,
  6. C J Justinich1,2
  1. 1
    Department of Anatomy and Cell Biology, Queen’s University, Kingston, Ontario, Canada
  2. 2
    Department of Pediatrics, Queen’s University, Kingston, Ontario, Canada
  3. 3
    Department of Pathology and Molecular Medicine, Queen’s University, Kingston, Ontario, Canada
  4. 4
    Department of Radiology, Queen’s University, Kingston, Ontario, Canada
  1. Correspondence to Dr C Justinich, Queen’s University, Kingston, ON, Canada K7L 3N6; justinic{at}kgh.kari.net

Abstract

This report describes the unusual case of a 12-year-old boy with multiple polyps in the oesophagus and concurrent eosinophilic oesophagitis (EoE). Polyps were of a fibrous-inflammatory composition featuring eosinophils, mast cells, hyperplastic epithelium and fibrosis, which are all features described with EoE. EoE is an increasingly recognised clinicopathological disorder characterised by large numbers of eosinophils infiltrating the oesophageal mucosa. Polyps in the oesophagus are rare, have not previously been associated with EoE, and may represent a new feature of the disease.

https://doi.org/10.1136/jcp.2009.066100

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    Footnotes

    • Funding This work was supported by a grant from the Physicians’ Services Incorporated Foundation (R 05–21, CJJ). We acknowledge support from Kingston General Hospital and the Queen’s University Gastrointestinal Diseases Research Unit.

    • Competing interests None.

    • Provenance and Peer review Commissioned; externally peer reviewed.

    • Patient consent Parental consent obtained.