Article Text

Download PDFPDF
Uveal melanoma metastasising to the heart after 39 years
  1. Kiran Jakate1,
  2. Bobby Yanagawa2,
  3. Robert J Cusimano2,
  4. Jagdish Butany1,3
  1. 1Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada
  2. 2Division of Cardiovascular Surgery, Toronto General Hospital/University Health Network, Toronto, Ontario, Canada
  3. 3Department of Pathology, Toronto General Hospital/University Health Network. Toronto, Ontario, Canada
  1. Correspondence to Dr Jagdish Butany, Department of Pathology, E4-301, Toronto General Hospital, Toronto, Ontario M5G 2C4, Canada; jagdish.butany{at}

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.


Ocular melanoma most often arises in the uvea and has several distinguishing characteristics from cutaneous melanoma including: dominant liver metastases, poor response to systemic therapy and late metastasis.1 We present a case of ocular melanoma, presenting after 39 years with liver and cardiac metastases (CM) to the right atrium and left ventricle. This is the longest time to CM from ocular or cutaneous melanoma that we could find in the English literature.


A 68-year-old male presented with progressive shortness of breath over months. He had a history of ocular melanoma diagnosed 39 years prior and treated with enucleation of his left eye. Medical records were not available, but the patient recalled the lesion was a spindle B tumour. The patient had no known cardiac disease. A short systolic ejection murmur …

View Full Text


  • Competing interests None.

  • Patient consent Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.