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- Papillary carcinoma
- MALT lymphoma
- Hashimoto's thyroiditis
- histopathology
- immunohistochemistry
- molecular pathology
- neoplasmas
- thyroid
Simultaneous occurrence of papillary carcinoma and lymphoma in the thyroid is extremely rare, only three cases having so far been reported.
In a 51-year-old woman with thyroid nodules, papillary carcinoma was diagnosed in an ultrasound-guided fine needle aspiration of a right lobe nodule. Subsequent thyroidectomy revealed a 1 cm large, Warthin-like papillary carcinoma (figure 1), whereas a 0.7 cm focus of classical type papillary carcinoma was found in the lower third of the right lobe. Hashimoto thyroiditis was also seen (figure 2). Moreover, a 1.2 cm area with scant thyroid follicles and large lymphoid follicles surrounded by small lymphocytes was found in the left lobe. The lymphoid infiltrate showed immunopositivity for both CD20 and CD43; …
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Competing interests None.
Provenance and peer review Not commissioned; externally peer reviewed.