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A 60-year-old woman presented with a painless lump in the left breast. A solitary movable mass in the left upper–outer quadrant of the breast was palpated on physical examination. It had a hard texture and a poorly defined boundary. Fine-needle aspiration revealed ovoid and spindle-shaped tumour cells with mildly pleomorphic nuclei that were approximately two-to-three times larger than a small lymphocyte (figure 1).
Fine-needle aspiration reveals uniform oval or spindle-shaped cells with a high nuclear-to-cytoplasmic ratio and indistinct borders. Endothelial-lined capillary vessels lie within fragments of tissue (H&E ×200).
The surgical specimen was a non-encapsulated solid mass that measured 4×4×3 cm. Cut sections were haemorrhagic and showed a well-defined tumour border (figure 2). Microscopic examination revealed a solid highly cellular tumour. The tumour cells had ill-defined membrane borders. Some tumour cells were epithelial like, and in many areas they were arranged …
Footnotes
Funding The research fund of Peking University People's Hospital.
Competing interests None.
Patient consent Obtained.
Provenance and peer review Not commissioned; externally peer reviewed.
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