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Carboxylesterase 1 (Ces1): from monocyte marker to major player
  1. Geraldine M Markey
  1. Correspondence to Geraldine M Markey, 23 Deramore Drive, Belfast BT9 5JR, UK; geraldinemarkey1939{at}


There are few, if any, enzymes that have been studied by, and have importance in, so many and varied disciplines as has monocyte esterase/Ces 1. In this review its involvement in the fields of histochemistry, haematology, toxicology, pharmacology, therapeutics, and tumour cell killing, immune surveillance and malignant disease, is briefly described.

  • Enzymes
  • genetics
  • haemato-oncology
  • macrophages
  • toxicology

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  • Competing interests None to declare.

  • Provenance and peer review Not commissioned; externally peer reviewed.