Article Text

Download PDFPDF
Adenomyoepithelioma of the breast: a review stressing its propensity for malignant transformation
  1. Malcolm M Hayes
  1. Correspondence to Professor Malcolm M Hayes, Department of Pathology, BC Cancer Agency, 600 West 10th Avenue, Vancouver, BC V5Z 4E6, Canada; mhayes{at}


This review describes the classification, clinical presentation, pathological features and clinical behaviour of adenomyoepithelioma (AME) of the breast. It is based on an extensive review of the literature and study of a collection of cases built up over a 17-year period at the British Columbia Cancer Agency. The diversity of the morphology encountered in both benign and malignant AME is described. The behaviour of malignant AME seems to be related to the grade of the malignant component.

  • Breast neoplasms
  • adenomyoepithelioma
  • pathology
  • breast cancer
  • breast pathology
  • cancer
  • histopathology
  • malignant tumours

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.


  • Competing interests None.

  • Provenance and peer review Not commissioned; not externally peer reviewed.