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Recurrent axillary lymphadenopathy with benign squamous epithelial inclusions in a female with no breast pathology
  1. Eleftherios Agorogiannis1,
  2. Mariam Rana1,
  3. Betania Mahler-Araujo2,
  4. Paul Meredith1,
  5. George Metaxas1
  1. 1Cambridge Breast Unit, Addenbrooke's Hospital, Cambridge, UK
  2. 2Department of Pathology, Addenbrooke's Hospital, Cambridge, UK
  1. Correspondence to Dr Eleftherios Agorogiannis, 10B Kingston House, Puddicombe Way, Cambridge, CB2 0AF, UK; eleftherios.agorogiannis{at}

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A middle-aged female presented with a 7-month history of a non-tender mobile lump in the right axilla. Ultrasonography demonstrated a 40×38 mm lymph node with no hilum. A smaller (28×25 mm) mammographically detected axillary lymph node had been resected from the patient's right axilla 3 years earlier, at which time histology reported a benign squamous epithelial cyst inclusion. The clinical and radiological breast examination was normal on both occasions.

Following a non-malignant, yet inconclusive, ultrasound-guided needle core biopsy result, the lymph node was surgically excised from the lower axilla (level 1) where it was attached on the serratus anterior muscle. Complete histological examination reported reactive changes and multiple cysts lined by keratinising squamous epithelium (figure 1), with no evidence of cellular atypia or …

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  • Contributors EA, MR, PM and GM were responsible for the patient's clinical care and recognised the rarity of her clinical entity. Additionally, EA and GM performed literature search and wrote the manuscript. BM-A analysed the histological slides. All authors read and approved the final version of the manuscript.

  • Competing interests None.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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