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Contributors YN analysed the data and prepared the manuscript. XX, HB, ZZ, BW and LY collected specimens and clinical data. MC carried out the genetic studies. HC conducted the immunohistochemical experiments. HZ was responsible for the diagnosis and revised the manuscript.
Competing interests None.
Patient consent Obtained.
Supported by National Natural Science Foundation of China (no. 30971148).
Provenance and peer review Not commissioned; externally peer reviewed.