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EGFR mutant-specific immunohistochemistry has high specificity and sensitivity for detecting targeted activating EGFR mutations in lung adenocarcinoma

Authors

  • W A Cooper Department of Tissue Pathology and Diagnostic Oncology, Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia School of Medicine, University of Western Sydney, Sydney, New South Wales, Australia PubMed articlesGoogle scholar articles
  • B Yu Department of Molecular and Clinical Genetics, Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia Sydney Medical School, University of Sydney, Sydney, New South Wales, Australia PubMed articlesGoogle scholar articles
  • P Y Yip Sydney Medical School, University of Sydney, Sydney, New South Wales, Australia Department of Oncology, Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia Kinghorn Cancer Centre and Garvan Institute of Medical Research, Sydney, New South Wales, Australia PubMed articlesGoogle scholar articles
  • C C Ng Department of Molecular and Clinical Genetics, Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia PubMed articlesGoogle scholar articles
  • T Lum Department of Tissue Pathology and Diagnostic Oncology, Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia PubMed articlesGoogle scholar articles
  • M Farzin Department of Anatomical Pathology and Northern Cancer Translational Research Unit, Royal North Shore Hospital, Sydney, New South Wales, Australia PubMed articlesGoogle scholar articles
  • R J Trent Department of Molecular and Clinical Genetics, Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia Sydney Medical School, University of Sydney, Sydney, New South Wales, Australia PubMed articlesGoogle scholar articles
  • B Mercorella Department of Molecular and Clinical Genetics, Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia PubMed articlesGoogle scholar articles
  • A Clarkson Department of Anatomical Pathology and Northern Cancer Translational Research Unit, Royal North Shore Hospital, Sydney, New South Wales, Australia PubMed articlesGoogle scholar articles
  • M R J Kohonen-Corish School of Medicine, University of Western Sydney, Sydney, New South Wales, Australia Kinghorn Cancer Centre and Garvan Institute of Medical Research, Sydney, New South Wales, Australia St Vincent's Clinical School, University of NSW, Sydney, New South Wales, Australia PubMed articlesGoogle scholar articles
  • L G Horvath Sydney Medical School, University of Sydney, Sydney, New South Wales, Australia Department of Oncology, Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia Kinghorn Cancer Centre and Garvan Institute of Medical Research, Sydney, New South Wales, Australia PubMed articlesGoogle scholar articles
  • J G Kench Department of Tissue Pathology and Diagnostic Oncology, Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia Sydney Medical School, University of Sydney, Sydney, New South Wales, Australia Kinghorn Cancer Centre and Garvan Institute of Medical Research, Sydney, New South Wales, Australia PubMed articlesGoogle scholar articles
  • B McCaughan Sydney Medical School, University of Sydney, Sydney, New South Wales, Australia Department of Cardiothoracic Surgery, Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia PubMed articlesGoogle scholar articles
  • A J Gill Sydney Medical School, University of Sydney, Sydney, New South Wales, Australia Department of Anatomical Pathology and Northern Cancer Translational Research Unit, Royal North Shore Hospital, Sydney, New South Wales, Australia PubMed articlesGoogle scholar articles
  • S A O'Toole Department of Tissue Pathology and Diagnostic Oncology, Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia Sydney Medical School, University of Sydney, Sydney, New South Wales, Australia Kinghorn Cancer Centre and Garvan Institute of Medical Research, Sydney, New South Wales, Australia PubMed articlesGoogle scholar articles
  1. Correspondence to Associate Professor Wendy Cooper, Tissue Pathology and Diagnostic Pathology, Royal Prince Alfred Hospital, Missenden Rd, Camperdown, NSW 2050, Australia; wendy.cooper{at}sswahs.nsw.gov.au
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Citation

Cooper WA, Yu B, Yip PY, et al
EGFR mutant-specific immunohistochemistry has high specificity and sensitivity for detecting targeted activating EGFR mutations in lung adenocarcinoma

Publication history

  • Received March 8, 2013
  • Revised April 8, 2013
  • Accepted May 9, 2013
  • First published June 11, 2013.
Online issue publication 
August 16, 2013

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