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Footnotes
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Contributors HJC: designed the research and wrote the manuscript; Y-JK, J-OJ, K-WB and JRL: performed the immunohistochemical analysis, collected and analysed data; HKJ: analysed and confirmed immunohistochemical data; MSO, YHC, W-JK, Se-HL, BKA and Su-HL: supervised the final manuscript.
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Funding This work was supported by the Korea Research Foundation Grant funded by the Korean Government (KRF-20090066740) and the National Research Foundation of Korea (NRF) grant funded by the Korean government (NRF-2013R1A1A4A01004996).
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Competing interests None.
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Ethics approval Both the collection and the analysis of all samples were approved by the Institutional Review Board of Kosin University Gospel Hospital. Informed consent was obtained from each patient enrolled in the study (IRB approval number: KUGH IRB 11-60).
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Provenance and peer review Not commissioned; externally peer reviewed.